This study was conducted to explore and compare perceptions of Subject Specialist Teachers about their role as a humanistic student guide. Subject specialists were taken from 28 male and 13 female higher secondary schools situated in Dera Ismail Khan, Khyber Pakhtunkhwa province, Pakistan. Structured questionnaire was used for data collection. As per the data analysis, it was concluded that most of the teachers did not possess proper awareness f a humanistic approach for the guidance of the student. Student guidance was almost absent due to lack of skills, resources, time specification for the purpose of the school administration and expertise. It was noticed that the situation in female higher secondary schools was almost the same as it was noted in the male schools as no significant difference of perception was found among male and female teachers. There was a need for proper training, and provision of resources for an appropriate guidance of the students.